On 1881 Census Elizabeth Whelton, formerly Brown, nee Cowlishaw is with her husband Charles Whelton and they are living next door to her son Francis Brown and her mother Lucy Cowlishaw.
I have been looking at some of the weekly and quarterly reports on Births and Deaths which appeared in the Sheffield newspapers in 1866 and 1867. It seems that Sheffield largely escaped the 1866 epidemic. London, Liverpool and some Welsh towns were the worst affected.